R. E. McCullumsmith
Latest
- Assessing the effects of antipsychotic medications on schizophrenia functional analysis: a postmortem proteome study
- Schizophrenia: a disorder of broken brain bioenergetics
- KRSA: An R package and R Shiny web application for an end-to-end upstream kinase analysis of kinome array data
- Strategies to identify candidate repurposable drugs: COVID-19 treatment as a case example
- Cellular, molecular, and therapeutic characterization of pilocarpine-induced temporal lobe epilepsy
- Fluoxetine as an anti-inflammatory therapy in SARS-CoV-2 infection
- Identification of candidate repurposable drugs to combat COVID-19 using a signature-based approach
- Using protein turnover to expand the applications of transcriptomics
- Similarities and dissimilarities between psychiatric cluster disorders
- Role of Astrocytes in Major Neuropsychiatric Disorders
- Emerging Kinase Therapeutic Targets in Pancreatic Ductal Adenocarcinoma and Pancreatic Cancer Desmoplasia
- Kinome Array Profiling of Patient-Derived Pancreatic Ductal Adenocarcinoma Identifies Differentially Active Protein Tyrosine Kinases
- A role for endothelial NMDA receptors in the pathophysiology of schizophrenia
- KEOPS complex expression in the frontal cortex in major depression and schizophrenia
- KEOPS complex expression in the frontal cortex in major depression and schizophrenia
- Consequences of NMDA receptor deficiency can be rescued in the adult brain
- Oxytocin's anti-inflammatory and proimmune functions in COVID-19: a transcriptomic signature-based approach
- Combining Neurobehavioral Analysis and In Vivo Photoaffinity Labeling to Understand Protein Targets of Methamphetamine in Casper Zebrafish
- Identification of new drug treatments to combat COVID19: A signature-based approach using iLINCS
- Signature-based approaches for informed drug repurposing: targeting CNS disorders
- Bilirubin remodels murine white adipose tissue by reshaping mitochondrial activity and the coregulator profile of peroxisome proliferator-activated receptor alpha
- Corticostriatal dysfunction and social interaction deficits in mice lacking the cystine/glutamate antiporter
- Adenosine Kinase Expression in the Frontal Cortex in Schizophrenia
- A bioinformatic inquiry of the EAAT2 interactome in postmortem and neuropsychiatric datasets
- Pioglitazone improves working memory performance when administered in chronic TBI
- Kinase network dysregulation in a human induced pluripotent stem cell model of DISC1 schizophrenia
- Measurement of lactate levels in postmortem brain, iPSCs, and animal models of schizophrenia
- Connectivity Analyses of Bioenergetic Changes in Schizophrenia: Identification of Novel Treatments
- Role of glutamatergic system and mesocorticolimbic circuits in alcohol dependence
- Neurotransmitter changes after traumatic brain injury: an update for new treatment strategies
- Chronic Dysregulation of Cortical and Subcortical Metabolism After Experimental Traumatic Brain Injury
- Sex differences in DEK expression in the anterior cingulate cortex and its association with dementia severity in schizophrenia
- Neuron-specific deficits of bioenergetic processes in the dorsolateral prefrontal cortex in schizophrenia
- Cell-subtype-specific changes in adenosine pathways in schizophrenia
- Defects in Bioenergetic Coupling in Schizophrenia
- The role of glutamate transporters in the pathophysiology of neuropsychiatric disorders
- Abnormalities of signal transduction networks in chronic schizophrenia
- Contrasting the Role of xCT and GLT-1 Upregulation in the Ability of Ceftriaxone to Attenuate the Cue-Induced Reinstatement of Cocaine Seeking and Normalize AMPA Receptor Subunit Expression
- Postsynaptic Density-95 Isoform Abnormalities in Schizophrenia
- Traumatic Brain Injury Induces Alterations in Cortical Glutamate Uptake without a Reduction in Glutamate Transporter-1 Protein Expression
- Glutamate Neurotransmission in Rodent Models of Traumatic Brain Injury
- Shaping plasticity: Alterations in glutamate transporter localization as a pathophysiological mechanism in severe mental illness
- Decreased protein S-palmitoylation in dorsolateral prefrontal cortex in schizophrenia
- Systematic evaluation of data-independent acquisition for sensitive and reproducible proteomics-a prototype design for a single injection assay
- Tyrosine hydroxylase localization in the nucleus accumbens in schizophrenia
- Cortical PGC-1alpha-Dependent Transcripts Are Reduced in Postmortem Tissue From Patients With Schizophrenia
- Cell-specific abnormalities of glutamate transporters in schizophrenia: sick astrocytes and compensating relay neurons?
- Glutamate transporter splice variant expression in an enriched pyramidal cell population in schizophrenia
- Changes in cortical N-methyl-D-aspartate receptors and post-synaptic density protein 95 in schizophrenia, mood disorders and suicide
- Evidence for schizophrenia as a disorder of neuroplasticity
- Decreased chloride channel expression in the dorsolateral prefrontal cortex in schizophrenia
- Postmortem brain: an underutilized substrate for studying severe mental illness
- Regulation of extrasynaptic glutamate levels as a pathophysiological mechanism in disorders of motivation and addiction
- Increased G protein-coupled receptor kinase (GRK) expression in the anterior cingulate cortex in schizophrenia
- Localization of excitatory amino acid transporters EAAT1 and EAAT2 in human postmortem cortex: a light and electron microscopic study
- Altered serine/threonine kinase activity in schizophrenia
- Abnormal partitioning of hexokinase 1 suggests disruption of a glutamate transport protein complex in schizophrenia
- Global signaling effects of a schizophrenia-associated missense mutation in neuregulin 1: an exploratory study using whole genome and novel kinome approaches
- Postmortem brain: an underutilized substrate for studying severe mental illness
- Update on the neurobiology of schizophrenia: a role for extracellular microdomains
- Abnormal N-linked glycosylation of cortical AMPA receptor subunits in schizophrenia
- Gene expression of glutamate metabolizing enzymes in the hippocampal formation in human temporal lobe epilepsy
- Abnormal expression of glutamate transporters in temporal lobe areas in elderly patients with schizophrenia
- AMPA receptor subunit expression in the endoplasmic reticulum in frontal cortex of elderly patients with schizophrenia
- Expression of equilibrative nucleoside transporter type 1 protein in elderly patients with schizophrenia
- Recent advances in targeting the ionotropic glutamate receptors in treating schizophrenia
- Regional differences in expression of beta-tubulin isoforms in schizophrenia
- Abnormal activity of the MAPK- and cAMP-associated signaling pathways in frontal cortical areas in postmortem brain in schizophrenia
- Endosomal trafficking of AMPA receptors in frontal cortex of elderly patients with schizophrenia
- Novel approaches to the study of postmortem brain in psychiatric illness: old limitations and new challenges
- Evidence for abnormal forward trafficking of AMPA receptors in frontal cortex of elderly patients with schizophrenia
- Vesicular glutamate transporter mRNA expression in the medial temporal lobe in major depressive disorder, bipolar disorder, and schizophrenia
- Abnormal glycosylation of EAAT1 and EAAT2 in prefrontal cortex of elderly patients with schizophrenia
- Decreased expression of NMDA receptor-associated proteins in frontal cortex of elderly patients with schizophrenia
- Expression of four housekeeping proteins in elderly patients with schizophrenia
- Abnormal expression of glutamate transporter and transporter interacting molecules in prefrontal cortex in elderly patients with schizophrenia
- Cortical expression of glial fibrillary acidic protein and glutamine synthetase is decreased in schizophrenia
- Altered vesicular glutamate transporter expression in the anterior cingulate cortex in schizophrenia
- Abnormal glutamate receptor expression in the medial temporal lobe in schizophrenia and mood disorders
- Expression of transcripts for myelination-related genes in the anterior cingulate cortex in schizophrenia
- Decreased NR1, NR2A, and SAP102 transcript expression in the hippocampus in bipolar disorder
- Expression of excitatory amino acid transporter interacting protein transcripts in the thalamus in schizophrenia
- Metabotropic glutamate receptor protein expression in the prefrontal cortex and striatum in schizophrenia
- Increased expression of glutaminase and glutamine synthetase mRNA in the thalamus in schizophrenia
- Schizophrenia as a disorder of neuroplasticity
- Effects of 6-cyano-7-nitroquinoxaline-2,3-dione on nicotinic receptor subunit transcript expression in the rat brain
- Expression of ARHGEF11 mRNA in schizophrenic thalamus
- Expression of transcripts for the vesicular glutamate transporters in the human medial temporal lobe
- Molecular abnormalities of the glutamate synapse in the thalamus in schizophrenia
- CC-chemokine receptor 2 required for bleomycin-induced pulmonary fibrosis
- Differential effects of antipsychotics on haloperidol-induced vacuous chewing movements and subcortical gene expression in the rat
- Striatal excitatory amino acid transporter transcript expression in schizophrenia, bipolar disorder, and major depressive disorder